AN ANTIHISTAMINE-LIKE SUBSTANCE (OR SUBSTANCES) IN EXTRACTS PREPARED FROM HUMAN TISSUES

Histamine and antihistamine substances.

Carcinogenic substances in human tissues.

Some of the problems presented by the carcinogenic substances that have been extracted from human tissues will be solved only when these compounds have been chemically identified and assayed. At the present time very difficult questions have been raised by the fact that the substances have been found in the tissues from some patients dead of cancer but not in others, sample of 67 human livers, ...

An inactive, prorenin-like substance in human kidney and plasma.

1. Plasma prorenin (inactive renin), which accounts for about 70% of the total renin in human plasma, was almost completely separated from active renin by affinity chromatography on Cibacron blue F3G-A-agarose. The slight residual renin activity present in the prorenin peak can be removed on concanavalin A-Sepharose, demonstrating that prorenin is completely inactive. 2. The renin activity of b...

IN VITRO STUDY OF AN ENDOGENOUS IMMUNOSUPPRESSOR FACTOR DERIVED FROM HUMAN OR BOVINE SERUM

The effects of the human and bovine LSF (derived from sera) as well as their purified fractions were studied on murine lymphocytes reactions indicated by blast transformation (BT) assay, mixed lymphocyte culture (MLC) and IgG synthesis. The results indicated that bovine lipid suppressor factor (LSF) has significant immunosuppressive activity on lymphocytes proliferation both in BT and MLC ...

Detection of an endotoxin-like substance during human plague bacteremia.